Analysis 2
- Wide variations in CD marker distribution.
- Tissue-related clusters are common
- Some markers are universally expressed (e.g. CD45), while others are lineage-specific.
Analysis 4
![]()
Number of significant CD markers (p < 0.05)
| B cells |
104 |
| Thymocytes |
74 |
| CD4 T cells |
51 |
| CD8 T cells |
46 |
- Table: B cells had the most significant markers, showing stronger activation changes.
- B cells: Tonsil B cells are more activated (CD69, CD80), while blood B cells mature gradually (CD11a, CD80).
- CD4 T cells: Mature from thymus to blood, losing CD10 and gaining CD25 and CD4_MEM-241.
- CD8 T cells: Move from active thymus cells to mature blood cells with higher CD27 and CD95.
Analysis 5
- CD4 and CD8 T cells go through parallel stages
- How
Count of significant CDs
| SP1ap |
24 |
| SP1am |
15 |
| Naive |
18 |
| CM |
23 |
| EM |
25 |
| TEMRA |
22 |